Author

Evie Fitzsimons

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Open access Aug 2026

Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment.

TFiT (tumor-reactive features in T cells), a transcriptional classifier that identifies tumor-reactive T cells and stratifies immunotherapy, but not chemotherapy, response across independent MM and AML cohorts, supporting its specificity for T cell-mediated tumor control.

N. Kehl, T. Wagner, Simon Steiger et al. · Cancer Cell · 1 citation