A transdiagnostic evaluation of adult temperamental profiles and their interactions with childhood adversities across major psychiatric disorder.
BACKGROUND Temperamental profiles and adverse childhood experiences (ACEs) have been reported in most major psychiatric disorders. However, the nature of this relationship is complex and under-studied. METHODS A total of 1162 individuals (N = 532 affected; N = 457 unaffected first-degree relatives (FDRs) and N = 173...