Author

F. B. Engel

2 papers indexed here

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Open access Oct 2026

A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity

T and B cell–mediated immunosurveillance of the central nervous system (CNS) can become maladaptive in multiple sclerosis (MS). Epstein–Barr virus (EBV) is a likely driver of MS, yet how exactly EBV-specific T cells contribute remains unclear. We generated an antigen-resolved atlas of blood and cerebrospinal fluid (CSF...

N. Kristensen, T. Tsaktanis, S. Frischholz et al. · bioRxiv · 0 citations

Open access Sep 2026

Integrative Bioinformatics Across Proliferative and Non-Proliferative Cell States Reveals Novel Cytokinesis Genes

The mammalian heart has no significant endogenous regenerative capacity, as mammalian cardiomyocytes undergo a last round of cell cycle after birth, becoming post-mitotic and polyploid. Consistent with this, cytokinesis inhibition in zebrafish impairs their cardiac regenerative capacity. Notably, re-induction of cell c...

M. Angeloni, Marina Leone, Marco Moraschini et al. · International Journal of Mol... · 0 citations