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Fabio Bennet Gätje

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Open access Oct 2026

A clinically annotated proteomic and histological resource of 1,000 colorectal cancers

Colorectal cancer (CRC) is heterogeneous, yet current classifications capture this heterogeneity only in part. Here we present a multimodal resource of 1,000 treatment-naïve CRC cases, the largest proteomically profiled CRC cohort to date, integrating deep proteomics, targeted genomics, whole-slide histopathology and c...

A. Qoku, N. Ullrich, F. Miranda et al. · 0 citations
Open access Aug 2026

Targeting addiction to HMGB2-driven transcriptional programs in pancreatic cancer.

A small molecule inhibitor is repurposed to interfere with its binding to DNA, restrict chromatin accessibility at promoters, and constrain tumor growth both in vitro and in vivo to show how increased HMGB2 availability represents a transcriptional addiction that fuels cell-cycle progression and growth.

Adi Danieli-Mackay, Ioanna Papadionysiou, Markos Tsitsianopoulos et al. · 0 citations

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