From 1,2-Diborylalkenes to Functionalized Indenols: Tandem Suzuki Coupling-Intramolecular Cyclization.
A concise and efficient domino strategy for the synthesis of symmetrically 2,3-disubstituted indenols has been developed via palladium-catalyzed Suzuki coupling of readily accessible 1,2-diborylalkenes with substituted 2-bromoaryl carbonyl compounds. The reaction proceeds efficiently, with palladium playing a dual role...