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Review Open access Sep 2026

The Role of Regulatory T Cells in Periodontitis With or Without Systemic Diseases: A Systematic Review

Findings do not establish a causal role for Treg modulation or support Treg-targeted therapies in current clinical practice, but suggest alterations in the balance between immunomodulatory Tregs and pro-inflammatory Th17 lymphocytes, together with changes in related cytokine profiles compared with healthy controls.

A. Inchingolo, M. C. Fatone, G. Marinelli et al. · 0 citations

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