Replicative and Air Pollution-Induced Senescence: Telomere Dysfunction, Mitochondrial Stress, and Modulatory Effects of Astragaloside IV in Endothelial and Vascular Smooth Muscle Cells
Telomere dysfunction and mitochondrial impairment are central drivers of vascular cell senescence and atherosclerosis, but their molecular interplay—especially under environmental stress—remains poorly defined. Fine particulate matter (PM) is an important contributor to vascular aging, but effective strategies to mitig...