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Oct 2026

Modular Synthesis of γ-Chloro Ketones through Carbochlorination of Alkenes Mediated by Copper(I) Photoredox Catalysis

γ-Chloro ketones are multifunctional synthons that serve as versatile linchpins for the rapid assembly of molecular complexity. Despite this strategic value, their broader adoption remains conspicuously limited as a consequence of the intrinsic challenges associated with their preparation. Herein, we report a visible...

F. Hagen, Sabrina L. Simmet, H. Stuntebeck et al. · 0 citations
Open access Sep 2026

Critical role of electrostatic interactions in protein kinetic stability: Kinetic studies of unfolding ubiquitin using SDS at varying pH values.

Protein stability in surfactant environments is crucial for various applications including industrial enzyme formulations. The interaction between Ubiquitin (UBI) and Sodium Dodecyl Sulfate (SDS) is investigated to understand the effect of pH (2-9.5) on the unfolding of UBI in SDS. We carried out kinetic studies in whi...

M. López Hernández, F. Hagen, Gouranga Manna et al. · 0 citations

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