Background: Skeletal muscle depletion and malnutrition are common in heart failure (HF) and are associated with poor outcomes. Whether imaging-derived skeletal muscle reserve and laboratory-based nutritional indices provide complementary prognostic information remains unclear. We evaluated the prognostic value of total...
Çetin Alak, H. E. Kaya, F. Hunutlu et al.· Journal of Clinical Medicine· 0 citations
Background/Objectives: Pulmonary arterial hypertension (PAH) risk tools do not jointly capture right ventricular adaptation, systemic oxygen balance, and nutritional reserve. We developed the three-component CORE-PH score and assessed its association with long-term mortality. Methods: This retrospective, single-center...
Çetin Alak, Furkan Fatih Yurdalan, F. Hunutlu et al.· Diagnostics· 0 citations
Background: Hypercalcemia of malignancy (HCM) is associated with poor short-term prognosis, particularly when it represents the initial manifestation of an underlying, as yet uncharacterized malignancy. Serum calcium concentration alone may not adequately capture the systemic biological burden associated with advanced...
Nevriye Gül Ada Tak, Hikmet Öztop, F. Hunutlu· Journal of Clinical Medicine· 0 citations
Background/Objectives: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous multisystem syndrome in which conventional cardiac measures may not fully capture systemic vulnerability. The Endothelial Activation and Stress Index (EASIX) is prognostic in other cardiovascular populations, but evidence i...
Çetin Alak, Kaan Turhan, F. Hunutlu et al.· Biomedicines· 0 citations
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