Background: Genomic, epigenomic, and proteomic data capture complementary aspects of cardiovascular disease biology, but the value of integrating these data for predicting multiple cardiovascular disease outcomes across ancestry groups remains uncertain. Methods: We derived disease-specific proteomic scores using 999 p...
P. Meyre, M. Chong, M. Pigeyre et al.· medRxiv· 0 citations
The high prevalence of underdiagnosed COPD and related poor outcomes suggest that a large burden of COPD is under-recognised and presents missed opportunities for early intervention that can modify disease trajectory and improve long-term health outcomes.
Mylinh Duong, En-Te Kang, S. Rangarajan et al.· Lancet Global Health· 0 citations
Higher epigenetic age and DNAm scores for CRP, frailty, and mortality were associated with increased risk, whereas higher diet-related DNAm scores were inversely associated, particularly for all-cause death.
P. Meyre, M. Chong, E. Shemesh et al.· medRxiv· 0 citations
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