Systematic Investigation on Particle and Pore Size Effects of Mesoporous Silica on Molecular Mobility and Physical Stability of Overloaded Amorphous Acetaminophen
Polymeric excipients are generally used for physical stabilization of amorphous drugs. However, a more strategic design of amorphous formulations is needed to reduce the amount of excipients, for which the use of mesoporous materials can be a promising option. In this study, mesoporous silica (MS) with various particle...