Author

F. Lima

2 papers indexed here

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Open access Sep 2026

Zika virus oncolytic signaling reverts immunosuppressive and angiogenic glioblastoma microenvironment in vitro and in vivo

Glioblastoma (GBM), the most aggressive primary brain tumor, remains refractory to conventional therapies, characterized by high relapse rates and an extremely poor clinical prognosis. Oncolytic viruses represent a promising therapeutic frontier; specifically, Zika virus (ZIKV) has shown potent oncolytic activity again...

Gabriella P. A. de Freitas, Jefferson H. Quintanilla, J. M. Janeiro et al. · bioRxiv · 0 citations

Open access Aug 2026

Cellular Prion Protein as a Novel Regulator of Vascular Plexus Stability During Retinal Angiogenesis

Angiogenesis is essential not only during embryogenesis but also in adult physiology and disease, relying on vascular endothelial growth factor (VEGF) gradients to guide tip cell sprouting. Cellular prion protein (PrPC), expressed in several neurovascular unit (NVU) cell types, regulates neuronal and astrocytic differe...

Bárbara Gomes da Rosa, F. Leser, Marco Aurélio Alves et al. · Neurochemical Research · 0 citations