The present study aimed to investigate the nephrotoxic effects of oxytetracycline (OTC) and to evaluate the protective role of vitamin E (Evit) through oxidative stress, inflammation, and autophagy pathways. A total of 28 rats were randomly assigned to four experimental groups: control, Evit, OTC, and OTC + Evit and tr...
Aydın Genç, F. M. Kandemir, E. Dalkılınç et al.· Laboratuvar Hayvanları Bilim...· 0 citations
AIM
Ketamine (KTM) is widely used in clinical settings for its anesthetic, analgesic, and antidepressant properties. However, prolonged or repeated KTM exposure can induce neurotoxicity through oxidative stress, neuroinflammation, and apoptotic mechanisms. This study investigated the neuroprotective effects of Chrysin...
Onur Karaca, Özge Kandemir, Hasan Şimşek et al.· Neurotoxicology and Teratolo...· 0 citations
SE was found to exert hepatoprotective effects against ENRO induced liver injury by reducing lipid peroxidation, strengthening antioxidant defense systems, and regulating inflammatory and autophagic responses.
Aydın Genç, F. M. Kandemir, E. Dalkılınç et al.· Veterinary Sciences and Prac...· 0 citations
FVP caused multifaceted oxidative, inflammatory, apoptotic, and hormonal damage in ovarian and uterine tissues, while BTN significantly reduced these effects, preserving tissue integrity and function.
R. Bülbül, Hasan Şimşek, N. Akaras et al.· Reproductive Sciences· 0 citations
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