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F. Ma

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Preprint Jul 2026

A safety-oriented hypothetico-deductive framework for AI-assisted differential diagnosis

The findings suggest that engineering diagnostic AI as a safety-oriented reasoning framework, rather than optimizing raw predictive accuracy alone, can provide a safer, more transparent, and clinically meaningful layer of bedside decision support for acute care workflows.

F. Ma, Mauro Giuffrè, D. Wright et al. · 0 citations
#artificial intelligence Preprint Jun 2026

Teaching agentic AI to learn expert reasoning for rare disease diagnosis

Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer; off-the-shelf large language models (LLMs) rank the correct disease first in only 35.4% of benchmark cases. Here we show that this expert reasoning can be converted into a scalable AI capability through a governed learning proc...

Minh-Ha Nguyen, Erica Gray, B. Schuler et al. · 0 citations

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