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Author

F. Martinelli-Boneschi

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Open access Sep 2026

Epigenetic Insights in Pediatric Multiple Sclerosis

Background and Objectives Pediatric-onset multiple sclerosis (PedMS) provides a unique opportunity to investigate MS pathogenesis because of the short interval between environmental exposures and disease onset. This study aimed to identify differentially methylated regions (DMRs) that mediate the interplay between envi...

Andrea Corona, Martina Tosi, A. Zollo et al. · 0 citations
Open access Sep 2026

Genome-wide association analyses highlight the neuronal contribution to multiple sclerosis susceptibility

Inhibitory neurons emerged as a key target cell type for MS-associated variants, with seven loci, including STAT3, displaying altered expression only in these cells, suggesting that MS susceptibility may reflect reduced central nervous system resilience to inflammatory challenges.

Lu Zeng, Atlas Khan, Kathryn C. Fitzgerald et al. · 0 citations

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