Nov 2026
Cannabidiol prevents fear extinction deficits caused by single prolonged stress in rats: possible involvement of serotoninergic, cannabinoid, and nitric mechanisms.
Post-traumatic stress disorder (PTSD) involves impaired extinction learning, autonomic and neuroendocrine dysregulation, and first-line selective serotonin reuptake inhibitors (SSRIs) show limited efficacy. We investigated effects and mechanisms of cannabidiol (CBD) on fear deficits induced by the single prolonged stre...
C. Vila-Verde, Mariana G. Fronza, D. Uliana et al.
· Neuropharmacology · 0 citations