545. Targeting negative and cognitive symptoms in schizophrenia: discussion of novel preclinical and clinical findings with evenamide
Abstract Background The recognition of hippocampal pyramidal neuron hyperexcitability as core pathological feature of schizophrenia has led to the idea that the hippocampus might be a promising target for therapeutic intervention (Lodge and Grace, 2011). However, the mechanism of action (MoA) of currently available ant...