Combining Clinical LAFOV PET/CT with a Digital Twin Providing Motion-Free Ground Truth Reveals Quantitative Trade-offs in Respiratory Motion Correction
Purpose: Respiratory motion remains a major source of quantitative bias in PET and becomes increasingly relevant for high-sensitivity long axial field-of-view (LAFOV) PET/CT. Although numerous respiratory motion correction (MoCo) methods have been proposed, their quantitative accuracy cannot be established clinically b...