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Author

F. Sousa

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6 papers indexed here

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Open access Oct 2026

Remnant cholesterol: an independent determinant of coronary artery disease and future cardiovascular events beyond traditional risk factors

Remnant cholesterol (RC) is a proven independent and causal risk factor for coronary artery disease (CAD), beyond LDL-C, HDL-C, triglycerides, diabetes, and other traditional risk factors. It reflects the cholesterol content of triglyceride-rich lipoproteins and is strongly associated with subclinical inflammatio...

F. Sousa, M. Mendonca, G. Abreu et al. · 0 citations
Open access Oct 2026

Association of cardiovascular-kidney-metabolic syndrome with cardiovascular mortality: a prospective cohort study in Madeira Island

Cardiovascular disease (CVD) results from interconnected metabolic and renal comorbidities that jointly increase atherosclerotic burden and mortality. The American Heart Association recently introduced the cardiovascular–kidney–metabolic (CKM) syndrome staging system, but its prognostic relevance remains under di...

F. Sousa, M. Mendonca, S. Freitas et al. · 0 citations
Open access Oct 2026

Insulin resistance metric and risk of all-cause mortality: a comparative population-based study in Portugal

Atherosclerotic cardiovascular diseases with cardiometabolic conditions have a high prevalence of comorbidities and an elevated mortality risk. Insulin resistance (IR) is a significant contributor to their pathogenesis. METS-IR assessors for IR are employed in clinical evaluations; however, their relationship wit...

M. Ferreira, M. Mendonca, G. Abreu et al. · 0 citations
Open access Oct 2026

Influence of invasive ischemic evaluation on mortality in patients with a new onset heart failure after myocardial infarction

New-onset heart failure (HF) after myocardial infarction (MI) identifies a high-risk population with increased morbidity and mortality, for whom early invasive ischemic evaluation is recommended. However, referral rates remain suboptimal, suggesting a potential care gap. Evaluate the proportion of patients...

M. Ferreira, M. Mendonca, F. E. Silva et al. · 0 citations
Open access Oct 2026

Nonlinear association of TyG index and METS-IR with cardiovascular mortality in cardiometabolic patients: a long-term cohort study

Cardiovascular diseases with cardiometabolic conditions have a high prevalence of comorbidities and an elevated mortality risk. Insulin resistance (IR) is a significant contributor to their pathogenesis. Several assessors for IR are employed in clinical evaluations; however, their relationship with mortality is i...

G. Abreu, M. Mendonca, M. Ferreira et al. · 0 citations
Open access Oct 2026

Central adiposity outperforms body mass index in predicting coronary artery disease: a prospective comparative study

Obesity is a well-established risk factor for coronary artery disease (CAD). Increasing evidence, however, indicates that obesity should not be regarded solely as a risk factor but as a chronic, multifactorial disease with complex metabolic and inflammatory consequences. A recent Commission (2025) proposed redefining...

G. Abreu, M. Mendonca, F. Sousa et al. · 0 citations

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