Background Central molecular mediators—including hypoxia-inducible factors (HIF-1α/HIF-2α), MYC, wild-type and mutant p53, NF-κB, STAT3, SREBPs, NRF2, and KRAS—orchestrate these pathways by linking nutrient availability to oncogenic signalling, epigenetic reprogramming, and immune-metabolic crosstalk within the tumour...
Rashid Mir, J. Barnawi, Naseh A. Algehainy et al.· Frontiers in Oncology· 0 citations
Background
The etiology of CAD is multifactorial, involving a complex interplay of genetic, environmental, and lifestyle factors, and CAD markedly increases the likelihood of impaired quality of life.
Aim
To identify potentially impactful genetic variants in patients with CAD that may influence the risk, severity, an...
Rashid Mir, M. F. Ullah, J. Javid et al.· Frontiers in Cardiovascular...· 0 citations
Therapeutic approaches employing mesenchymal stem cells (MSCs) have emerged as a promising avenue for investigating treatments for neurological disorders. This strategy aims to capitalize on the biological properties of MSCs to support the repair of damaged neural tissue and modulate pathological processes. This review...
M. C. Jamali, Alaa Shafie, A. J. Alqahtani et al.· Stem cell research & therape...· 0 citations
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