BACKGROUND
Negative expectations towards the future are frequently observed in patients with major depressive disorder (MDD) and linked to less favourable outcomes like worse treatment response and suicidal behaviours. Despite clinical significance, the neurobiological underpinnings of negative expectations remain larg...
Laila Noor, F. Stein, K. Brosch et al.· Journal of Affective Disorde...· 0 citations
The moderating effect of CR on the brain network-cognition association provides a neurobiological rationale for this vulnerability and supports incorporating CR into routine clinical assessment to guide risk stratification and personalized treatment planning.
M. Gruber, Henrike Renaud, M. Mauritz et al.· Psychotherapy and Psychosoma...· 0 citations
Major depressive disorder (MDD) has been associated with accelerated structural brain aging, yet whether this reflects a pre-existing neurobiological vulnerability, a dynamic acute state effect, or an accumulating biological residual remains unresolved. Across two longitudinal cohorts (N=3220), including a unique sampl...
M. Konowski, A. Kraus, J. Goltermann et al.· medRxiv· 0 citations
This study provides the first data-driven evidence for a potential causal role of gut microbiota in the pathophysiology of depression in humans, and employs state-of-the-art causal inference tools within Judea Pearl's framework.
L. Fehse, A. H. Ribeiro, N. Winter et al.· Gut microbes· 0 citations
It is found that standard benchmarks do not adequately capture the strengths of the dataset, but expert judgment shows that SQPsych makes LLMs significantly better at therapist roleplaying.
Doan Nam Long Vu, Rui Tan, L. Mary Moench et al.· arXiv.org· 5 citations· ⚡2
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