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Author

F. Triulzi

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Nov 2025

DTI‐ALPS Primarily Reflects White Matter Diffusion Dispersion and Microstructural Heterogeneity in Neurodegeneration: Insights From Multi‐Modal MRI

Factor analysis indicated that DTI-ALPS clustered with MA and ODI rather than forming a distinct factor, suggesting that DTI-ALPS primarily reflects WM diffusion dispersion and heterogeneity rather than glymphatic flow in the context of neurodegeneration.

L. Sacchi, Giovanni Farruggio, Giorgio Bocca et al. · 1 citation
#diffusion models Open access Sep 2026

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS).

CP enlargement is associated with reduced DTI-ALPS and greater WML burden, but the contribution of glymphatic impairment remains uncertain, and alternative mechanisms may contribute to these findings.

L. Sacchi, Valentina Veronesi, Giorgio Bocca et al. · 0 citations

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