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F. Türkan

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Open access Oct 2026

Synthesis, Biological Evaluation, and Molecular Dynamics Studies of Novel 1,2,4-Triazole-Functionalized Benzene-Sulfonate Derivatives as Potential Enzyme Inhibitors and Cytotoxicity in HepG2 Cells

Background/Objectives: In this study, novel benzenesulfonate derivatives containing a 1,2,4-triazole ring were synthesized. Methods: Their molecular structures were characterized by IR, 1H NMR, and 13C NMR spectroscopy, together with Q-TOF LC/MS analyses. For compounds 5b and 5d, the available mass spectrometric data w...

Y. Ünver, F. Türkan, H. Güler et al. · 0 citations
Open access 2026

Biochemical and Pharmacological Evaluation of Selected Artemisia Species with Antioxidant and Antimicrobial Activities

The genus Artemisia is recognized for its diverse secondary metabolites and therapeutic potential; however, evaluating species from the Nakhchivan region is significant for mapping their regional bioactive profiles. This study investigated the chemical characteristics, antioxidant activity, and antimicrobial effects of...

S. Rahimova, Gülsüm Merve Boyraci, Oktay Yıldız et al. · 0 citations
Open access Aug 2026

Integrated network pharmacology and in vitro/in silico evaluation of the bioactive potential of Gundelia komagenensis fırat extracts

Network pharmacology suggested that the identified phenolics may regulate disease-related pathways through AP-1/NF-κB-associated targets and chlorogenic acid emerged as a key multi-target candidate warranting further experimental validation.

Abdülmelik Aras, Yunus Dağhan, Alpaslan Bayrakdar et al. · 0 citations
Sep 2026

A synthetic Benzothiazole-Thiourea Derivative with Multi-Target Potential Activity for Alzheimer's Disease: Antioxidant Properties and Mechanistic Insights.

The antioxidant activity and the potential effects of H74 on multiple targets associated with Alzheimer's disease (AD) were investigated and molecular docking results suggested that H74 might act as a potential inhibitor to these enzymes.

A. Lahouel, Kamel Harrouche, E. Oğuz et al. · 0 citations
Sep 2026

Crystal structure, intermolecular interactions, Hirshfeld surface analysis, theoretical studies and biological evaluation of (E)-5-(benzyloxy)-2-{[(2,5-dimethoxyphenyl)imino]methyl}phenol, a new Schiff base.

Results indicate an enzyme-dependent inhibitory profile rather than uniformly superior activity relative to the reference inhibitors, and quantum theory of atoms in molecules (QTAIM) analysis was performed to characterize selected intra- and intermolecular interactions.

Nadir Ghichi, R. Lemoui, Ahmed Abderrahim Yahiaouid et al. · 0 citations

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