Author

F. Urra

3 papers indexed here

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Open access Aug 2026

Recombinant BaMtx Preserves the Biological Properties of a Lys49 Phospholipase A2 from Bothrops atrox and Reveals Differential Responses in Tumor and Non-Tumor Cell Models

Lys49 phospholipase A2 (Lys49-PLA2) homologues are catalytically inactive snake venom toxins with diverse biological activities, but their functional characterization requires recombinant production strategies to overcome the limitations inherent to native venom-derived proteins. Here, we produced recombinant BaMtx (rB...

D. Torrejón, A. Regalado, Alex Proleón et al. · Toxins · 0 citations

Review Sep 2026

Enzymatic and non-enzymatic proteins from Bothrops snake venoms, their anticancer activity, and translational challenges in oncovenomics: A review.

Overall, the available evidence indicates that Bothrops venom proteins represent promising sources of bioactive anticancer scaffolds; however, significant translational challenges remain.

Ana Gabriela Amado-Argüelles, A. Yarlequé, Dan E. Vivas-Ruiz et al. · International Journal of Bio... · 0 citations

Open access Aug 2026

Beyond the full-length toxin: The metalloprotease domain of Pictolysin-III retains key functional properties and cellular activity.

Snake venom metalloproteinases are major determinants of viperid venom pathology, but the specific contribution of their metalloprotease domain to toxin function remains insufficiently defined. Here, we produced and characterized the metalloprotease domain of Pictolysin-III, a P-III metalloproteinase from Bothrops pict...

A. Roque, D. Torrejón, Alex Proleón et al. · Biomedicine & pharmacotherap... · 0 citations