Fa-Liang An

Pyridones and macrocyclic pyrrolidones from marine fungal PKS-NRPS hybrids: biosynthetic origin, bioactivities, and synthetic advances.

Covering: 2002-2025Marine fungi have emerged as a prolific source of structurally unprecedented and biologically potent secondary metabolites, and hybrid polyketide synthase-non-ribosomal peptide synthase (PKS-NRPS) enzymes mainly from marine fungi like symbiotic Aspergillus and deep-sea Penicillium, represent an excep...