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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Fabian B. H. Rehm

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Open access Jul 2026

Continuous site-directed mutagenesis and selection in Escherichia coli

This work demonstrates a distinct paradigm for library generation through efficient transfer of genetic elements to recipient cells bearing libraries of retron editors, efficient editing of cargo genes in recipient cells, and continuous iteration of the conjugation-editing cycles with selection for recipients in sequen...

Fabian B. H. Rehm, Martin Spinck, Jason W. Chin · 0 citations
Open access Jul 2026

Continuous target-specific mutagenesis and rapid gene evolution by diversity-generating retroelements in Escherichia coli

DGRs can be installed in E. coli and reprogrammed for the continuous, iterative mutagenesis of user-defined target genes, and the DGR template RNA can be reprogrammed for gene- and residue-specific mutagenesis, leaving untargeted, adjacent residues unchanged.

Yang Liu, Yang-Qi Gu, Ganesh Agam et al. · 0 citations

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