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Author

Fabiana De Franco

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Review Open access Aug 2026

Programmed cell death-1: from a T-cell immune checkpoint to a regulator of Natural Killer cell biology

The molecular mechanisms governing PD-1 expression and signaling, its contribution to immune dysfunction in cancer and chronic diseases, and the potential implications of targeting the PD-1 axis to enhance both adaptive and innate antitumor immunity are discussed.

Fabiana De Franco, Marco Greppi, Valentina Obino et al. · 0 citations

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