Author

Fabrizio Di Costanzo

2 papers indexed here

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Open access Aug 2026

Gene expression analyses of immune tumor microenvironment in advanced renal cell carcinoma patients based on response to immunotherapy (Meet-URO 18 I-TME study)

Despite many treatment strategies available for metastatic renal cell carcinoma (mRCC), predictive biomarkers of response to immunotherapy are still needed. In this context, growing efforts have been devoted to translational research, especially focusing on the immune tumor microenvironment (I-TME). The Me...

S. E. Rebuzzi, F. Catalano, Francesca Schiavi et al. · Cancer Immunology and Immuno... · 0 citations

Review Open access Aug 2026

Molecular biomarkers in metastatic clear cell renal cell carcinoma treated with first-line immune combinations: a systematic review of phase III randomized clinical trials by Meet-URO group

Immune checkpoint inhibitor (ICI)–based combinations represent the standard first-line treatment for metastatic clear cell renal cell carcinoma (mRCC), although robust biomarkers for treatment selection remain undefined. We conducted a systematic review to identify biomarkers assessed in randomized clinical trials (RCT...

A. A. Valsecchi, M. Maffezzoli, M. Cursano et al. · Cancer Metastasis Review · 0 citations