Fabrizio Di Giovanni

Behavioral and spectral electroencephalographic biomarkers of epileptogenesis, disease progression, and drug resistance in a longitudinal lithium-pilocarpine model of temporal lobe epilepsy.

Temporal lobe epilepsy (TLE) is linked to progressive alterations in brain network dynamics, leading to behavioral comorbidities and emergence of drug resistance; yet the underlying mechanistic and synaptic substrates remain incompletely understood. Here, we performed longitudinal phase-specific characterization of net...