F. G. Saqallah

Cycloalkane-Fused 5H-Pyrido[3,2-b]indol-4-amines: Synthesis, Characterization, Molecular Docking, and In Vitro Cell-Viability Evaluation

A four-step synthetic route to functionalized cycloalkane-fused 5H-pyrido[3,2-b]indol-4-amines was developed from substituted 2-aminobenzonitriles. Initial N-alkylation with bromoacetonitrile was performed in a choline chloride/urea deep eutectic solvent, followed by K2CO3-promoted cyclization to give 3-aminoindole-2-c...