Author

Fahriye Duzagac

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Open access Aug 2026

Exercise-associated epigenetic remodeling and TCR repertoire dynamics in Lynch syndrome carriers

Summary Lynch syndrome (LS) carriers are at elevated cancer risk. Emerging evidence suggests that exercise may serve as a non-pharmacologic preventive strategy, yet the epigenetic and immunological mechanisms underlying its protective effects in this population remain unclear. Here, we perform integrative multi-omics p...

Jin-Ling Wang, Nan Deng, Abel Martel-Martel et al. · iScience · 0 citations

Open access Sep 2026

Characterization of circulating neoantigen-specific T cell responses and public T cell receptors shaping immune memory in Lynch syndrome carriers.

The architecture of circulating neoantigen-specific immune memory in LS is defined and public TCRs are highlighted as candidates for immune monitoring and immunoprevention.

Fahriye Duzagac, Nan Deng, Jin-Ling Wang et al. · Cell Reports Medicine · 0 citations