Fan-Qian Yang

A vicious cycle of microglial dysfunction: bridging synaptic pruning and neuroinflammation across the neurodevelopmental continuum

It is proposed that microglia occupy a central position at the interface of these processes because of their dual roles in circuit remodeling and immune surveillance and highlights disease-modifying therapeutic strategies aimed at restoring microglial homeostasis to potentially mitigate the self-sustaining pathology in...