Integrating Network Pharmacology and Metabolomics to Elucidate the Mechanism of Allopurinol in Hyperuricemia Treatment.
This study integrated network pharmacology and metabolomics to investigate the mechanism of allopurinol in treating hyperuricemia (HUA). Therapeutic targets were identified by screening drug and disease databases. A drug-target-disease network was constructed and validated by molecular docking using Cytoscape. A mouse...