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Author

Fan Yang

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2 papers indexed here

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Sep 2026

Neuroglobin positively regulates YTHDF3 to restore mitophagy and suppress ferroptosis in sevoflurane-induced developmental neurotoxicity.

In vitro assays demonstrated that NGB alleviates sevoflurane-triggered mitochondrial damage and neuronal death via two separate cascades: NGB restores mitophagy and suppresses ferroptosis by interacting with and positively regulating the protein expression of YTHDF3, whereas its intrinsic antioxidant activity improves...

Jia-Xin Yang, Rong-Li Guan, Jin-Yang Liu et al. · 0 citations
Review Open access Jul 2026

ADAR-mediated RNA editing in CNS disorders: from pathogenic mechanisms to therapeutic opportunities

This review critically synthesizes existing evidence and thoroughly assesses the unique molecular fingerprints of ADAR dysregulation across several CNS disorders, emphasizing recurring themes such as Alu RNA hypo-editing, induction of innate immunity, and GRIA2 editing, which can cause excitotoxicity.

Fu-Shuang Zheng, Rong-Li Guan, Xiaojin Yu et al. · 0 citations

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