Biomimetic arsenic trioxide nanoplatform induces Caspase-3/GSDME pyroptosis and remodels the glioma immune microenvironment
Glioma (GBM) is characterized by severe invasiveness and grim clinical outcomes. The therapeutic efficacy of conventional treatments is severely constrained by the blood-brain barrier (BBB), while the immunosuppressive tumor microenvironment (TME) further compromises treatment responsiveness. In GBM, abnormal expre...