Dihydromyricetin attenuates cerebral ischemia-reperfusion injury associated with modulation of sirtuin 1-forkhead box O3 signaling and mitophagy.
BACKGROUND Ischemic stroke remains associated with substantial neurological disability, and effective strategies for cerebral ischemia-reperfusion injury (CIRI) are limited. Dihydromyricetin (DHM) has shown neuroprotective properties in experimental neurological disorders, but its effects and associated molecular mecha...