Review
Open access
Aug 2026
Immune modulation in gastric cancer: from macrophage polarization to immunotherapy
Gastric cancer remains a highly lethal malignancy characterized by late diagnosis, limited therapeutic responsiveness, and a profoundly immunosuppressive tumor microenvironment. Among the diverse cellular components shaping this ecosystem, tumor-associated macrophages (TAMs) have emerged as central orchestrators of gas...
Xiao-Feng Cui, Xue-Rui Wang, Nan Jiang et al.
· Frontiers in Immunology · 0 citations