Open access
Sep 2026
Positive-sense RNA viruses using subgenomic RNAs (sgRNAs) cause severe crop losses, yet this conserved feature has rarely been exploited for antiviral engineering. Here, we constructed a virus-activated synthetic immune circuit, wherein viral sgRNA production drives host defense responses via a translation inhibition–t...
Zhao-Lei Li, Jing Zhang, Xin-Xin Yang et al.
· Science Advances · 0 citations
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Open access
Aug 2026
It is demonstrated that targeting the OSB1-ALD1 defense module represents a widespread and conserved geminivirus mechanism to subvert chloroplast immunity.
Zuxian Pan, Yu-Zhen Mei, Fang-Fang Li et al.
· Phytopathology Research · 0 citations
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Open access
Jul 2026
This study demonstrates that expression of tomato leaf curl New Delhi virus CP confers effective resistance against tomato yellow leaf curl China virus (TYLCCNV), another prominent geminivirus, and uncovers a novel mechanism by which a viral effector antagonizes viral CP-mediated host resistance during mixed viral infe...
Shi Wu, Yuzhen Mei, Yuan Chen et al.
· Phytopathology Research · 0 citations
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Aug 2026
This study expands Cas12a targeting scope in plants and provides the first evidence for Cas12-mediated MMEJ-based large-fragment deletion in plants.
Yaolong Wang, Huanhuan Xu, Wenjun Lu et al.
· New Phytologist · 1 citation
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