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Fangfang Li

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Open access Sep 2026

Specific and efficient translation inhibition–transcription activation resistance module against viruses in plants

Positive-sense RNA viruses using subgenomic RNAs (sgRNAs) cause severe crop losses, yet this conserved feature has rarely been exploited for antiviral engineering. Here, we constructed a virus-activated synthetic immune circuit, wherein viral sgRNA production drives host defense responses via a translation inhibition–t...

Zhao-Lei Li, Jing Zhang, Xin-Xin Yang et al. · 0 citations
Open access Jul 2026

A geminivirus betasatellite subverts the viral coat protein-mediated resistance to promote systemic infection

This study demonstrates that expression of tomato leaf curl New Delhi virus CP confers effective resistance against tomato yellow leaf curl China virus (TYLCCNV), another prominent geminivirus, and uncovers a novel mechanism by which a viral effector antagonizes viral CP-mediated host resistance during mixed viral infe...

Shi Wu, Yuzhen Mei, Yuan Chen et al. · 0 citations

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