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Fanlu Meng

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Aug 2026

Phospholipid-Mimetic Amphiphilic Polyion Complexes Enable Intracellular Oligonucleotide Delivery under Charge-Neutral Conditions.

Here, we report phospholipid-mimetic cationic copolymers that facilitate intracellular oligonucleotide delivery at a net charge-neutral polymer/DNA mixing ratio. Conventional nucleic acid delivery nanocarriers are mainly internalized through endocytosis, which often leads to endosomal sequestration and nucleic acid deg...

Fanlu Meng, Tatsuro Goda · 0 citations

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