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Author

Fareed Ahmad

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Open access Oct 2026

Bortezomib induces ROS-dependent mitochondrial apoptosis and suppresses SKP2 signaling in cutaneous T-cell lymphoma cells

Cutaneous T-cell lymphomas (CTCL) are skin-homing T-cell malignancies characterized by recurrent disease, therapeutic resistance and limited durable treatment responses in advanced stages. Although the proteasome inhibitor bortezomib has demonstrated activity in CTCL, the molecular pathways associated with its an...

K. Prabhu, M. Suleman, Ummu Habeeba et al. · 0 citations
Open access Jul 2026

Protein Arginine Methyltransferase-5 Inhibition Induces Growth Arrest and Death in Triple-Negative Breast Cancer Cells

It is suggested that PRMT5 inhibition by CMP5 is associated with reduced TNBC cell viability, impaired migration, increased expression of apoptosis-associated regulators and enhanced apoptotic cell death as measured by Annexin V/PI analysis in vitro.

Majdi Al-Alawneh, Fareed Ahmad, A. M. Abdallah et al. · 0 citations

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