Characterization of structural variants in KOLF2.1J iPSCs and their potential impact on forebrain organoid differentiation.
The KOLF2.1J human induced pluripotent stem cell (iPSC) line was created as a reference for neurological disease modeling. Previous genotyping efforts identified several large structural variants (SVs), raising questions about their potential impact on neuronal differentiation. Here, we identified 37 additional SVs usi...