Unraveling the role of glucosamine: Fructose-6-phosphate aminotransferase (GFAT) in Entamoeba histolytica: A comprehensive exploration through biochemical, reverse genetic, and Metabolomic analyses.
Entamoeba histolytica is a protozoan parasite that causes amebiasis in humans. Its life cycle consisting of two stages: the proliferative trophozoite, which is responsible for clinical symptoms, and the dormant cyst, which mediates disease transmission. The cyst wall is primarily composed of chitin, a polymer of β-1,4-...