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Fatemeh Babaei

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2 papers indexed here

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Open access Aug 2026

TRIM9 Determines Sex-Specific β-Amyloid/Cellular Prion Protein/mGluR5 Complex Formation and Pathological Signaling in Alzheimer’s Disease Mice

Biological sex is a major determinant of Alzheimer’s disease prevalence, yet the molecular mechanisms underlying sex-specific vulnerability remain largely unknown. Metabotropic glutamate receptor 5 (mGluR5) functions as a co-receptor for β-amyloid (Aβ42) oligomer/cellular prion protein (PrPC)-mediated pathogenic signal...

Fatemeh Babaei, Fatemeh A. Panahi, Tash-Lynn L. Colson et al. · 0 citations
Open access Aug 2026

β-Arrestin2 Drives Sex-Specific Akt/GSK3β Signaling, Aβ Pathology, and Cognitive Decline in Alzheimer’s Disease Mice

Sex is a major determinant of Alzheimer’s disease risk and progression, yet the molecular mechanisms underlying this dimorphism remain poorly defined, limiting the development of sex-informed therapeutics. β-Arrestin2 is a pervasive, multifunctional regulator common to a host of G protein-coupled receptors (GPCRs) in t...

Fatemeh A. Panahi, Fatemeh Babaei, Tash-Lynn L. Colson et al. · 0 citations

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