Aug 2026
Design, synthesis, thymidylate synthase docking, and biological evaluation of Pyrazolone- and Benzothiazole-functionalized Bis(acetamide) derivatives in Caco-2 and HDF cells.
DPPH reactivity and cellular response followed different trends, and the modest differential sensitivity, limited compound series, and suboptimal purity of R3 support cautious interpretation and further mechanistic validation using adequately purified compound batches.
Ihab Abbas Taher, F. W. Askar, Fatin Fadhel Al-Kazzaz
· Bioorganic chemistry (Print) · 0 citations