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Feby Anastasya Sirait

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Review Open access Aug 2026

A REVIEW ON STRUCTURAL OPTIMIZATION OF BETALACTAM ANTIBIOTICS AND DEVELOPMENT OF ?ETALACTAMASE INHIBITORS AGAINST ESBL-MEDIATED RESISTANCE

Extended-Spectrum ?-Lactamase (ESBL)-mediated antimicrobial resistance has become a major challenge in treating Gram-negative bacterial infections by reducing the efficacy of ?-lactam antibiotics. This review evaluates the structural modification strategies of ?-lactam antibiotics and the development of next-generation...

Feby Anastasya Sirait, T. Rahmania · 0 citations

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