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Federica Barbieri

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Open access Jul 2026

Repurposing Triamterene as Chloride Intracellular Channel 1 Inhibitor via Ligand-Based Approach: A Novel Adjuvant Treatment for Glioblastoma.

Triamterene emerges as a repurposed anti-glioblastoma agent with higher potency and tumor selectivity than metformin, together with its well-known favorable pharmacokinetic profile, which makes TMT a promising candidate for clinical translation in glioblastoma patients.

Federica Barbieri, F. Cianci, B. Tremonti et al. · 0 citations

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