Pimozide enhances antigen cross-presentation and promotes cytotoxic CD8+ T cell immunity by stimulating dendritic cells
The activation of cytotoxic CD8 + T cells requires antigen presentation in the context of major histocompatibility complex class I (MHC-I). While endogenous antigens can directly access this pathway, the priming of CD8 + T cells against exogenous antigens—such as those derived from tumors or internalized pathogen...