Open access
Sep 2026
Adenovirus early proteins E1A and E3-19K reveal separable regulatory states of the ER stress sensor IRE1a.
These findings show that canonical IRE1a activation hallmarks can be mechanistically separated during viral infection, revealing distinct AdV-regulated IRE1a activation states with discrete upstream and downstream signaling outputs.
Debkanya Sengupta, S. Srivastava, Fedor Bezrukov et al.
· Molecular Biology of the Cel... · 0 citations