Fei-Fei Dai

Macrophages as orchestrators of gut-organ axis crosstalk: immunometabolic reprogramming and host-directed therapy in sepsis

Sepsis is a life-threatening syndrome driven by a dysregulated host response to infection. Among the numerous contributory factors, the gut microbiota and its metabolites are increasingly recognized as potential modulators of systemic inflammation, acting through multiple gut-organ axes. Within this network, macrophage...