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Review Open access Oct 2026

The Lipid Paradox in Chronic Liver Disease: Integrative Evidence From Intrahepatic Transcriptomics and Population-based Cohorts.

Background/Aims Chronic liver disease (CLD) is associated with major metabolic disturbances. Although an elevated atherogenic index of plasma (AIP) reflects cardiometabolic risk, progressive liver dysfunction may instead be accompanied by lipid depletion, suggesting a "lipid paradox." We aimed to investigate its intrah...

Shu-Qiong Su, Zhi-Ming Chen, Ying-Tong Ye et al. · 0 citations
Nov 2026

miR-200c-3p: An Adjunct Chronic Heart Failure Risk Marker Modulating Cardiomyocyte Hypertrophic Transcription and Cardiac Fibroblast Fibrosis.

This study evaluated circulating microRNA-200c-3p (miR-200c-3p) for diagnosis and prognosis in chronic heart failure (CHF) and its regulatory roles in cardiomyocyte hypertrophy and myocardial fibrosis in vitro. A single-center prospective cohort included 150 CHF patients and 80 healthy controls, with CHF stratified int...

Fei Li, Bao-Feng Jiang · 0 citations

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